12 Things Cardiologists Think Hospitalists Need to Know
fraction have outcomes over the longer haul similar to those with heart failure with reduced ejection fraction. And in preserved ejection fraction cases, the contributing illnesses must be addressed.
"We really can't exercise a thought economy that just says, 'Extrapolate the evidence-based therapies for heart failure with reduced ejection fraction to heart failure with preserved ejection fraction' and expect good outcomes," Dr. Yancy says. "That's not the case. We don't have an evidence base to substantiate that."
He says one or more common comorbidities (e.g. atrial fibrillation, hypertension, obesity, diabetes, renal insufficiency) are present in 90% of patients with preserved ejection fraction. Treatment of those comorbidities—for example, rate control in afib patients, lowering the blood pressure in hypertension patients—has to be done with care.
"We should recognize that the therapy for this condition, albeit absent any specifically indicated interventions that will change its natural history, can still be skillfully constructed," Dr. Yancy says. "But that construct needs to reflect the recommended, guideline-driven interventions for the concomitant other comorbidities."
6) Patients With Heart Failure With Preserved Ejection
fraction have outcomes over the longer haul similar to those with heart failure with reduced ejection fraction. And in preserved ejection fraction cases, the contributing illnesses must be addressed.
"We really can't exercise a thought economy that just says, 'Extrapolate the evidence-based therapies for heart failure with reduced ejection fraction to heart failure with preserved ejection fraction' and expect good outcomes," Dr. Yancy says. "That's not the case. We don't have an evidence base to substantiate that."
He says one or more common comorbidities (e.g. atrial fibrillation, hypertension, obesity, diabetes, renal insufficiency) are present in 90% of patients with preserved ejection fraction. Treatment of those comorbidities—for example, rate control in afib patients, lowering the blood pressure in hypertension patients—has to be done with care.
"We should recognize that the therapy for this condition, albeit absent any specifically indicated interventions that will change its natural history, can still be skillfully constructed," Dr. Yancy says. "But that construct needs to reflect the recommended, guideline-driven interventions for the concomitant other comorbidities."
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