Association of SFRP4 With T2D in Patients With Stable CAD
This prospective study shows that higher SFRP4 concentrations are associated with T2DM and the metabolic syndrome in well-treated patients with coronary artery disease. SFRP4 concentrations are a novel marker of impaired glucose and triglyceride metabolism, but do not predict cardiovascular outcome in patients with stable coronary artery disease.
Further research is necessary to elucidate the relevance of SFRP4 levels in healthy people and patients with cardiovascular disease and its prognostic value for diabetes and cancer.
Conclusions
This prospective study shows that higher SFRP4 concentrations are associated with T2DM and the metabolic syndrome in well-treated patients with coronary artery disease. SFRP4 concentrations are a novel marker of impaired glucose and triglyceride metabolism, but do not predict cardiovascular outcome in patients with stable coronary artery disease.
Further research is necessary to elucidate the relevance of SFRP4 levels in healthy people and patients with cardiovascular disease and its prognostic value for diabetes and cancer.
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