Multiple Biopsies and Radical Prostatectomy Outcomes
There were no significant differences between the two groups in age, body mass index, prostate volume, preoperative PSA, total cores during last biopsy and maximum percent cancer on core biopsy. The median number of biopsies in the multiple biopsy group was two, which was statistically significantly different when compared with the single biopsy group (P<0.001). The median interval between (last) biopsy date and date of surgery was 78 days and 82 days for the multiple and single biopsy groups, respectively (P=0.897) (Table 1).
We found no effect on postoperative continence as a result of multiple biopsies, with rates of 84% (83%) and 94% (96%) for the single (multiple) biopsy groups at 3 and 6 months, respectively (P=0.88; P=0.77) (Table 2). However, multiple biopsy patients had worse postoperative erectile function at 3 months, though this was not statistically significant, with 43% of such patients being potent compared with 64% of single biopsy patients (P=0.25). Potency recovery at 6 months was significantly worse in the multiple biopsy group (57% versus 80%, P=0.03) (Table 3).
There were very few patients with positive surgical margins to compare whether oncologic outcomes varied based on whether multiple biopsies were taken preoperatively or not. Console time was not significantly different between the multiple and single biopsy groups (103 min versus 96 min, P=0.4). Hematocrit drop (on postoperative day 1 compared with time of surgery) showed nonstatistically significant less bleeding in the single biopsy group (3.4% versus 1.7%, P=0.82) (Table 4).
Results
There were no significant differences between the two groups in age, body mass index, prostate volume, preoperative PSA, total cores during last biopsy and maximum percent cancer on core biopsy. The median number of biopsies in the multiple biopsy group was two, which was statistically significantly different when compared with the single biopsy group (P<0.001). The median interval between (last) biopsy date and date of surgery was 78 days and 82 days for the multiple and single biopsy groups, respectively (P=0.897) (Table 1).
We found no effect on postoperative continence as a result of multiple biopsies, with rates of 84% (83%) and 94% (96%) for the single (multiple) biopsy groups at 3 and 6 months, respectively (P=0.88; P=0.77) (Table 2). However, multiple biopsy patients had worse postoperative erectile function at 3 months, though this was not statistically significant, with 43% of such patients being potent compared with 64% of single biopsy patients (P=0.25). Potency recovery at 6 months was significantly worse in the multiple biopsy group (57% versus 80%, P=0.03) (Table 3).
There were very few patients with positive surgical margins to compare whether oncologic outcomes varied based on whether multiple biopsies were taken preoperatively or not. Console time was not significantly different between the multiple and single biopsy groups (103 min versus 96 min, P=0.4). Hematocrit drop (on postoperative day 1 compared with time of surgery) showed nonstatistically significant less bleeding in the single biopsy group (3.4% versus 1.7%, P=0.82) (Table 4).
SHARE
