Use of Proton Pump Inhibitors After Antireflux Surgery
In a population-based register study, we found that risk of using PPI 5 year after ARS was greater than 50% and increased to more than 80% during follow-up. The risk of becoming a long-term PPI user was more than 50%. The extent of PPI use was much greater than previously shown in clinical trials and suggested that the effect of ARS on reflux symptoms should be interpreted with caution. Patients should be made aware that long-term PPI therapy is often necessary after ARS.
Conclusion
In a population-based register study, we found that risk of using PPI 5 year after ARS was greater than 50% and increased to more than 80% during follow-up. The risk of becoming a long-term PPI user was more than 50%. The extent of PPI use was much greater than previously shown in clinical trials and suggested that the effect of ARS on reflux symptoms should be interpreted with caution. Patients should be made aware that long-term PPI therapy is often necessary after ARS.
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