Numerous academic, medical and commercial applications, especially clinical research requires Monoclonal Antibodies in the process of their research. Several diagnostic tests, which are necessary for determining small amounts of drugs, toxins or hormones, for e.g. those used in pregnancy test kits, which require the presence of anti-bodies. From many other more known diagnostic processes or methodologies, which use these, is the diagnosis of AIDS by the ELISA test. The radioimmunodetection and radioimmunotherapy of cancer amongst which, certain new methods can even target only the cell membranes of cancerous cells also extensively depends upon and uses this methodology of Sequencing. The problem of organ rejection in patients, who have had organ transplants, has seen successful treatments developed is called as OKT3, which is an anti-body to the T3 antigen produced by T cells of the human immune mechanism. During the month of November in 1997, the FDA approved Ritoxin, a new cancer drug derived from the results and implementations of this technology. A strain of single pathogen such as Neisseria gonorrhoeae have been successfully classified using this methodology. Quite a few traditionally considered "untreatable" viral diseases have found solutions developed using Monoclonal Sequencing. With the pace at which current clinical research is growing, several research specialists constitute the opinion that such sequencing could be an important tool in the race to defeat HIV virus, and cure AIDS.

In the field of molecular biological research, its use is for determining the existence of antigen binding residues, and the nature of such antigen binding residues. These have become an important base in understanding and deploying research in biochemistry, molecular biology, and medicine. Monoclonal antibodies (mAb or moAb) are structurally identical monospecific antibodies. A specific type of B-lymphocytes produces these, which are all clones generated from a single parent cell. This method is deployed as it makes possible for synthesizing monoclonal anti-bodies, which specifically bind to a given substance €" almost any substance €" for detecting or purifying that substance. From the several sequencing methods, protein-sequencing method like Edman degradation, MS, HPLC/MS, etc. are more commonly used for deriving results. This process can be accomplished using several methods adopted worldwide, many of which are exorbitantly expensive. Alternatively, DNA sequencing is a relatively, cheaper technology for application in the sequencing process.

Our unmatched strength and expansive knowledge base in this highly skilled area of research helps accelerate your discovery and validation process. Our pioneering services have garnered us the position of a recognized leader in Monoclonal Antibody Sequencing. We provide for deriving a sequence from any antibody producing cell line. From a select few revered names in the business of protein sequencing, we are one of the companies to have also sequenced dead hybridomal cells. For more than 8 years, we have delivered more than 500 sequences for a variety of species including mouse, rat, bovine, human guinea pig, hamster, rabbits and human antibody secreting EBV cell lines. For any given kind of application, you can rest assured of our sequencing technology for quality, consistency and accurate results.