Occlusive Arterial Disease after Radiotherapy for Testicular Cancer
Radiation injury to arterial occlusion is a rare and late complication of radiotherapy. Numerous adverse reactions may occur secondary to radiation therapy. A well-known side effect is radiation-induced occlusive lesions and the enhancement of normally occurring atherosclerosis. We report a case of symptomatic right iliac and femoral artery occlusion after radiation therapy for carcinoma of the testis.
Arterial occlusion owing to radiotherapy is a rare but important ischemia situation in the exposed extremity. The vascular effects of radiation therapy are particularly challenging clinical problems and characteristically manifest after a long latency period. Radiation arteriopathy usually develops between 6 and 20 years after the radiotherapy. Clinical and experimental data suggest that radiation predisposes patients to atherosclerotic change by causing endothelial damage. We report a patient who presented with severe right lower limb ischemia following previous radiotherapy for testis carcinoma.
Abstract and Introduction
Abstract
Radiation injury to arterial occlusion is a rare and late complication of radiotherapy. Numerous adverse reactions may occur secondary to radiation therapy. A well-known side effect is radiation-induced occlusive lesions and the enhancement of normally occurring atherosclerosis. We report a case of symptomatic right iliac and femoral artery occlusion after radiation therapy for carcinoma of the testis.
Introduction
Arterial occlusion owing to radiotherapy is a rare but important ischemia situation in the exposed extremity. The vascular effects of radiation therapy are particularly challenging clinical problems and characteristically manifest after a long latency period. Radiation arteriopathy usually develops between 6 and 20 years after the radiotherapy. Clinical and experimental data suggest that radiation predisposes patients to atherosclerotic change by causing endothelial damage. We report a patient who presented with severe right lower limb ischemia following previous radiotherapy for testis carcinoma.
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