Minor Side Effects

• Some minor side effects are usually not considered to be cause for alarm since they tend to subside as the body gets used to the medication. However, should they intensify or persist, medical assistance might be necessary. These side effects include vomiting, moderate nausea, upset stomach, diarrhea, swelling or sores around the genital or rectal areas, difficulty swallowing, swollen tongue, vaginal discharge or itchiness, and white sores or patches on the lips or inside of the mouth.
  
  

Severe Side Effects

• Side effects of Doxy-D that are considered severe include yellowing or pale skin, dark urine, disorientation, confusion, weakness, fever, extreme headaches, feeling lightheaded, dizziness, blurry vision, chills, flu-like symptoms, aches, extreme upper stomach pain that extends all the way to the back, rapid heart rate, red rash, peeling or blistering skin, appetite loss, bleeding or bruising easily and decreased urination (or not urinating at all).
  
  People who experience any of these should immediately cease taking the medicine and get emergency medical attention.
  
  

Pregnancy and Nursing

• Women who are pregnant are advised to not use Doxy-D because of potential harm to the unborn infant, such as permanent tooth discoloration. Also, nursing women should avoid the medicine because it is excreted into the breast milk and can harm your baby.
  
  Doxy-D can decrease the effectiveness of birth control pills, so women should use a back-up method to avoid getting pregnant.
  
  

Drug Interactions

• Drug interactions can occur when more than one drug is taken at a time, and can cause negative side effects or decrease or increase the effectiveness of one or all of the medicines. Some drugs or nutritional supplements that often lead to interactions with Doxy-D include Accutane, medicines that lower cholesterol, minerals such as magnesium, zinc, calcium that are found in supplements, penicillin, antibiotics (like Trimox and Dynapen) and antacids (such as Rolaids, Maalox and Tums).
  
  

Overdose

• Signs of possible overdose include vomiting, nausea and diarrhea. If any of these side effects occur immediately after taking more than your appropriate amount of Doxy-D, it is very likely that you have overdosed and you should seek medical help immediately. These signs would generally be more severe than the other typical, similar side effects of the medication.