The Management of Cirrhosis in Women
Although epidemiologic studies of women with cirrhosis in the US are lacking, it is estimated that compared to men, cirrhosis in women is less common and associated with lower mortality. Women are thought to represent less than 40% of all patients with cirrhosis in the US; indeed, 38% of the subjects listed for liver transplantation (LT) are female. These estimates are similar to recent data from twenty-three European countries. The incidence of cirrhosis in women over the age of 50 years in the United Kingdom is estimated at 26 per 100 000 women per year; extended to the US population, this would represent an incidence of over 13 000 cases per year. Data from Center for Disease Control show that over 11 000 women (and about 20 000 men) died of chronic liver disease and cirrhosis in 2010. Thus, although less common than in men, cirrhosis in women still represents a significant burden of disease.
Background
Although epidemiologic studies of women with cirrhosis in the US are lacking, it is estimated that compared to men, cirrhosis in women is less common and associated with lower mortality. Women are thought to represent less than 40% of all patients with cirrhosis in the US; indeed, 38% of the subjects listed for liver transplantation (LT) are female. These estimates are similar to recent data from twenty-three European countries. The incidence of cirrhosis in women over the age of 50 years in the United Kingdom is estimated at 26 per 100 000 women per year; extended to the US population, this would represent an incidence of over 13 000 cases per year. Data from Center for Disease Control show that over 11 000 women (and about 20 000 men) died of chronic liver disease and cirrhosis in 2010. Thus, although less common than in men, cirrhosis in women still represents a significant burden of disease.
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