Low-Grade Central Nervous System Tumors
Low-grade tumors of the central nervous system constitute 15 to 35% of primary brain tumors. Although this category of tumors encompasses a number of different well-characterized entities, low-grade tumors constitute every tumor not obviously malignant at initial diagnosis. In this brief review, the authors discuss the pathological classification, diagnostic procedures, treatment, and possible pathogenic mechanisms of these tumors. Emphasis is given in the neuroradiological and pathological features of the several entities.
Low-grade gliomas of the brain represent a large proportion of primary brain tumors, ranging from 15 to 35% in most reported series. They include a remarkable diversity of lesions, all of which have been lumped together under the heading of "low-grade glioma." This category includes virtually every tumor of glial origin that is not overtly malignant at the time of initial diagnosis.
Low-grade tumors of the central nervous system constitute 15 to 35% of primary brain tumors. Although this category of tumors encompasses a number of different well-characterized entities, low-grade tumors constitute every tumor not obviously malignant at initial diagnosis. In this brief review, the authors discuss the pathological classification, diagnostic procedures, treatment, and possible pathogenic mechanisms of these tumors. Emphasis is given in the neuroradiological and pathological features of the several entities.
Low-grade gliomas of the brain represent a large proportion of primary brain tumors, ranging from 15 to 35% in most reported series. They include a remarkable diversity of lesions, all of which have been lumped together under the heading of "low-grade glioma." This category includes virtually every tumor of glial origin that is not overtly malignant at the time of initial diagnosis.
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